, Katherine Heigl as Isobel "Izzie" Stevens, Justin Chambers as Alex Karev, TR Knight as George O'Malley, Chandra Wilson as Miranda Bailey, James Pickens, Jr. as Richard Webber, Sara Ramirez as Callie Torres, Eric Dane as Mark Sloan, Chyler Leigh as Lexie Grey and Kevin McKidd as Owen Hunt. Guest stars Jessica Capshaw as Dr. Arizona Robbins, Michael Rady as Mike Shelley, Wendy Hoopes as Tricia, Erin Cahill as Meg, Susane E. Lee as Beth, Brandon Scott as Intern Ryan and Loretta Devine as ...
Chyler Leigh
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